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Inhibition of Histo-blood Group Antigen Binding as a Novel Strategy to Block Norovirus Infections

Noroviruses (NoVs) are the most important viral pathogens that cause epidemic acute gastroenteritis. NoVs recognize human histo-blood group antigens (HBGAs) as receptors or attachment factors. The elucidation of crystal structures of the HBGA-binding interfaces of a number of human NoVs representing...

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Detalles Bibliográficos
Autores principales: Zhang, Xu-Fu, Tan, Ming, Chhabra, Monica, Dai, Ying-Chun, Meller, Jarek, Jiang, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716607/
https://www.ncbi.nlm.nih.gov/pubmed/23894462
http://dx.doi.org/10.1371/journal.pone.0069379