Inactive DNMT3B Splice Variants Modulate De Novo DNA Methylation

Inactive DNA methyltransferase (DNMT) 3B splice isoforms are associated with changes in DNA methylation, yet the mechanisms by which they act remain largely unknown. Using biochemical and cell culture assays, we show here that the inactive DNMT3B3 and DNMT3B4 isoforms bind to and regulate the activi...

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Detalles Bibliográficos
Autores principales: Gordon, Catherine A., Hartono, Stella R., Chédin, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716610/
https://www.ncbi.nlm.nih.gov/pubmed/23894490
http://dx.doi.org/10.1371/journal.pone.0069486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716610/
https://www.ncbi.nlm.nih.gov/pubmed/23894490
http://dx.doi.org/10.1371/journal.pone.0069486

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