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MMP-9 and CXCL8/IL-8 Are Potential Therapeutic Targets in Epidermolysis Bullosa Simplex

Epidermolysis bullosa refers to a group of genodermatoses that affects the integrity of epithelial layers, phenotypically resulting in severe skin blistering. Dowling-Meara, the major subtype of epidermolysis bullosa simplex, is inherited in an autosomal dominant manner and can be caused by mutation...

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Detalles Bibliográficos
Autores principales: Lettner, Thomas, Lang, Roland, Klausegger, Alfred, Hainzl, Stefan, Bauer, Johann W., Wally, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716611/
https://www.ncbi.nlm.nih.gov/pubmed/23894602
http://dx.doi.org/10.1371/journal.pone.0070123