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Proteolysis Controls Endogenous Substance P Levels

Substance P (SP) is a prototypical neuropeptide with roles in pain and inflammation. Numerous mechanisms regulate endogenous SP levels, including the differential expression of SP mRNA and the controlled secretion of SP from neurons. Proteolysis has long been suspected to regulate extracellular SP c...

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Detalles Bibliográficos
Autores principales: Mitchell, Andrew J., Lone, Anna Mari, Tinoco, Arthur D., Saghatelian, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716696/
https://www.ncbi.nlm.nih.gov/pubmed/23894327
http://dx.doi.org/10.1371/journal.pone.0068638