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Proteolysis Controls Endogenous Substance P Levels
Substance P (SP) is a prototypical neuropeptide with roles in pain and inflammation. Numerous mechanisms regulate endogenous SP levels, including the differential expression of SP mRNA and the controlled secretion of SP from neurons. Proteolysis has long been suspected to regulate extracellular SP c...
Autores principales: | Mitchell, Andrew J., Lone, Anna Mari, Tinoco, Arthur D., Saghatelian, Alan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716696/ https://www.ncbi.nlm.nih.gov/pubmed/23894327 http://dx.doi.org/10.1371/journal.pone.0068638 |
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