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Transgenically mediated shRNAs targeting conserved regions of foot-and-mouth disease virus provide heritable resistance in porcine cell lines and suckling mice

Foot-and-mouth disease virus (FMDV) is responsible for substantial economic losses in livestock breeding each year, and the development of new strategies is needed to overcome the limitations of existing vaccines and antiviral drugs. In this study, we evaluated the antiviral potential of transgenic...

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Detalles Bibliográficos
Autores principales: Jiao, Ye, Gong, Xiuli, Du, Junzheng, Liu, Mingqiu, Guo, Xinbing, Chen, Linlin, Miao, Weinan, Jin, Tao, Chang, Huiyun, Zeng, Yitao, Zheng, Zhaoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716715/
https://www.ncbi.nlm.nih.gov/pubmed/23822604
http://dx.doi.org/10.1186/1297-9716-44-47