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Engineering Grp170-based immune modulators for cancer immunotherapy

We have recently demonstrated that glucose-regulated protein 170 (Grp170), a stress-responsive molecular chaperone of the endoplasmic reticulum, can be exploited to stimulate anticancer immunity due to its superior antigen chaperoning and delivering capacity. The immune remodeling of the tumor micro...

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Detalles Bibliográficos
Autores principales: Yu, Xiaofei, Wang, Xiang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716734/
https://www.ncbi.nlm.nih.gov/pubmed/23894699
http://dx.doi.org/10.4161/onci.24385