Promoting natural killer cell functions by recombinant immunoligands mimicking an induced self phenotype

Immunoligands for stimulatory natural killer (NK)-cell receptors can be targeted to the surface of malignant cells by fusing them to antibody fragments. Mimicking an “induced-self” phenotype, such recombinant immunoligands signal danger, trigger NK-cell cytotoxicity and synergistically enhance antib...

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Detalles Bibliográficos
Autores principales: Kellner, Christian, Gramatzki, Martin, Peipp, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716743/
https://www.ncbi.nlm.nih.gov/pubmed/23894708
http://dx.doi.org/10.4161/onci.24481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716743/
https://www.ncbi.nlm.nih.gov/pubmed/23894708
http://dx.doi.org/10.4161/onci.24481

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