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Promoting natural killer cell functions by recombinant immunoligands mimicking an induced self phenotype
Immunoligands for stimulatory natural killer (NK)-cell receptors can be targeted to the surface of malignant cells by fusing them to antibody fragments. Mimicking an “induced-self” phenotype, such recombinant immunoligands signal danger, trigger NK-cell cytotoxicity and synergistically enhance antib...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716743/ https://www.ncbi.nlm.nih.gov/pubmed/23894708 http://dx.doi.org/10.4161/onci.24481 |