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Synchronous apoptosis in established tumors leads to the induction of adaptive immunity

Understanding the immune response to the death of malignant cells is critical for the development of therapeutic strategies designed to stimulate the immune system against cancer. We have developed an inducible caspase-3-mediated death switch model to explore the effects of apoptosis on the host imm...

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Detalles Bibliográficos
Autores principales: Honeychurch, Jamie, Dive, Caroline, Illidge, Timothy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716746/
https://www.ncbi.nlm.nih.gov/pubmed/23894711
http://dx.doi.org/10.4161/onci.24501