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The role of FOXP3 in disease progression in colorectal cancer patients

The transcription factor forkhead box P3 (FOXP3) has been identified as a marker of CD4(+)CD25(+) regulatory T cells and is a key determinant of their immunosuppressive functions. FOXP3 has indeed been shown to limit antitumor immune responses during tumor progression. In addition, by expressing FOX...

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Detalles Bibliográficos
Autores principales: Grimmig, Tanja, Kim, Mia, Germer, Christoph-Thomas, Gasser, Martin, Waaga-Gasser, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716747/
https://www.ncbi.nlm.nih.gov/pubmed/23894712
http://dx.doi.org/10.4161/onci.24521