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TCC: an R package for comparing tag count data with robust normalization strategies
BACKGROUND: Differential expression analysis based on “next-generation” sequencing technologies is a fundamental means of studying RNA expression. We recently developed a multi-step normalization method (called TbT) for two-group RNA-seq data with replicates and demonstrated that the statistical met...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716788/ https://www.ncbi.nlm.nih.gov/pubmed/23837715 http://dx.doi.org/10.1186/1471-2105-14-219 |