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TCC: an R package for comparing tag count data with robust normalization strategies

BACKGROUND: Differential expression analysis based on “next-generation” sequencing technologies is a fundamental means of studying RNA expression. We recently developed a multi-step normalization method (called TbT) for two-group RNA-seq data with replicates and demonstrated that the statistical met...

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Detalles Bibliográficos
Autores principales: Sun, Jianqiang, Nishiyama, Tomoaki, Shimizu, Kentaro, Kadota, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716788/
https://www.ncbi.nlm.nih.gov/pubmed/23837715
http://dx.doi.org/10.1186/1471-2105-14-219