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Boolean network-based model of the Bcl-2 family mediated MOMP regulation

BACKGROUND: Mitochondrial outer membrane permeabilization (MOMP) is one of the most important points in the majority of apoptotic signaling cascades and it is controlled by a network of interactions between the members of the Bcl-2 family. METHODS: To understand the role of individual members of thi...

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Detalles Bibliográficos
Autores principales: Tokar, Tomas, Turcan, Zdenko, Ulicny, Jozef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716804/
https://www.ncbi.nlm.nih.gov/pubmed/23767791
http://dx.doi.org/10.1186/1742-4682-10-40