Cargando…

Trimethoxy-benzaldehyde levofloxacin hydrazone inducing the growth arrest and apoptosis of human hepatocarcinoma cells

BACKGROUND: In order to search for new structural modification strategies on fluoroquinolones, we have designed and synthesized a series of fluoroquinolone derivatives by linking various hydrazine compounds to the C-3 carboxyl group of levofloxacin and assessed their anticancer activities. Several n...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Jin-ping, Shi, Zhen-yu, Liu, Shi-meng, Kang, Yu-hua, Hu, Guo-qiang, Huangfu, Chao-shen, Deng, Jin-bo, Liu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716872/
https://www.ncbi.nlm.nih.gov/pubmed/23819802
http://dx.doi.org/10.1186/1475-2867-13-67