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Trimethoxy-benzaldehyde levofloxacin hydrazone inducing the growth arrest and apoptosis of human hepatocarcinoma cells
BACKGROUND: In order to search for new structural modification strategies on fluoroquinolones, we have designed and synthesized a series of fluoroquinolone derivatives by linking various hydrazine compounds to the C-3 carboxyl group of levofloxacin and assessed their anticancer activities. Several n...
Autores principales: | Sun, Jin-ping, Shi, Zhen-yu, Liu, Shi-meng, Kang, Yu-hua, Hu, Guo-qiang, Huangfu, Chao-shen, Deng, Jin-bo, Liu, Bin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716872/ https://www.ncbi.nlm.nih.gov/pubmed/23819802 http://dx.doi.org/10.1186/1475-2867-13-67 |
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