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LocARNAscan: Incorporating thermodynamic stability in sequence and structure-based RNA homology search

BACKGROUND: The search for distant homologs has become an import issue in genome annotation. A particular difficulty is posed by divergent homologs that have lost recognizable sequence similarity. This same problem also arises in the recognition of novel members of large classes of RNAs such as snoR...

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Detalles Bibliográficos
Autores principales: Will, Sebastian, Siebauer, Michael F, Heyne, Steffen, Engelhardt, Jan, Stadler, Peter F, Reiche, Backofen, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716875/
https://www.ncbi.nlm.nih.gov/pubmed/23601347
http://dx.doi.org/10.1186/1748-7188-8-14