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Low Expression of miR-196b Enhances the Expression of BCR-ABL1 and HOXA9 Oncogenes in Chronic Myeloid Leukemogenesis

MicroRNAs (miRNAs) can function as tumor suppressors or oncogene promoters during tumor development. In this study, low levels of expression of miR-196b were detected in patients with chronic myeloid leukemia. Bisulfite genomic sequencing PCR and methylation-specific PCR were used to examine the met...

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Detalles Bibliográficos
Autores principales: Liu, Yue, Zheng, Wenling, Song, Yanbin, Ma, Wenli, Yin, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716876/
https://www.ncbi.nlm.nih.gov/pubmed/23894305
http://dx.doi.org/10.1371/journal.pone.0068442