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Hypothalamic S-Nitrosylation Contributes to the Counter-Regulatory Response Impairment following Recurrent Hypoglycemia

AIMS: Hypoglycemia is a severe side effect of intensive insulin therapy. Recurrent hypoglycemia (RH) impairs the counter-regulatory response (CRR) which restores euglycemia. During hypoglycemia, ventromedial hypothalamus (VMH) production of nitric oxide (NO) and activation of its receptor soluble gu...

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Detalles Bibliográficos
Autores principales: Fioramonti, Xavier, Deak, Adam, Deshpande, Srinidhi, Carneiro, Lionel, Zhou, Chunxue, Sayed, Nazish, Orban, Branly, Berlin, Joshua R., Pénicaud, Luc, Leloup, Corinne, Beuve, Annie, Routh, Vanessa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716881/
https://www.ncbi.nlm.nih.gov/pubmed/23894333
http://dx.doi.org/10.1371/journal.pone.0068709