Cargando…

Evolution of the myosin heavy chain gene MYH14 and its intronic microRNA miR-499: muscle-specific miR-499 expression persists in the absence of the ancestral host gene

BACKGROUND: A novel sarcomeric myosin heavy chain gene, MYH14, was identified following the completion of the human genome project. MYH14 contains an intronic microRNA, miR-499, which is expressed in a slow/cardiac muscle specific manner along with its host gene; it plays a key role in muscle fiber-...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhuiyan, Sharmin Siddique, Kinoshita, Shigeharu, Wongwarangkana, Chaninya, Asaduzzaman, Md, Asakawa, Shuichi, Watabe, Shugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716903/
https://www.ncbi.nlm.nih.gov/pubmed/24059862
http://dx.doi.org/10.1186/1471-2148-13-142