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Disruption of rimP-SC, encoding a ribosome assembly cofactor, markedly enhances the production of several antibiotics in Streptomyces coelicolor

BACKGROUND: Ribosome assembly cofactor RimP is one of the auxiliary proteins required for maturation of the 30S subunit in Escherichia coli. Although RimP in protein synthesis is important, its role in secondary metabolites biosynthesis has not been reported so far. Considering the close relationshi...

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Detalles Bibliográficos
Autores principales: Pan, Yuanyuan, Lu, Cheng, Dong, Hailing, Yu, Lingjun, Liu, Gang, Tan, Huarong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716926/
https://www.ncbi.nlm.nih.gov/pubmed/23815792
http://dx.doi.org/10.1186/1475-2859-12-65