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Platelet-derived growth factor-A regulates lung fibroblast S-phase entry through p27(kip1) and FoxO3a
BACKGROUND: Secondary pulmonary alveolar septal formation requires platelet derived growth factor (PDGF-A) and platelet derived growth factor receptor-alpha (PDGFRα), and their regulation influences alveolar septal areal density and thickness. Insufficient PDGFRα expression in lung fibroblasts (LF)...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717055/ https://www.ncbi.nlm.nih.gov/pubmed/23819440 http://dx.doi.org/10.1186/1465-9921-14-68 |