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Platelet-derived growth factor-A regulates lung fibroblast S-phase entry through p27(kip1) and FoxO3a

BACKGROUND: Secondary pulmonary alveolar septal formation requires platelet derived growth factor (PDGF-A) and platelet derived growth factor receptor-alpha (PDGFRα), and their regulation influences alveolar septal areal density and thickness. Insufficient PDGFRα expression in lung fibroblasts (LF)...

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Detalles Bibliográficos
Autores principales: McGowan, Stephen E, McCoy, Diann M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717055/
https://www.ncbi.nlm.nih.gov/pubmed/23819440
http://dx.doi.org/10.1186/1465-9921-14-68