NF-κB and IRF7 Pathway Activation by Epstein-Barr Virus Latent Membrane Protein 1

The principal Epstein-Barr virus (EBV) oncoprotein, Latent Membrane Protein 1 (LMP1), is expressed in most EBV-associated human malignancies. LMP1 mimics CD40 receptor signaling to provide infected cells with constitutive NF-κB, MAP kinase, IRF7, and PI3 kinase pathway stimulation. EBV-transformed B...

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Detalles Bibliográficos
Autores principales: Ersing, Ina, Bernhardt, Katharina, Gewurz, Benjamin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717723/
https://www.ncbi.nlm.nih.gov/pubmed/23793113
http://dx.doi.org/10.3390/v5061587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717723/
https://www.ncbi.nlm.nih.gov/pubmed/23793113
http://dx.doi.org/10.3390/v5061587

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