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Identification of acetylation-dependent regulatory mechanisms that govern the oncogenic functions of Skp2

The Skp2 (S-phase kinase associated protein 2) oncoprotein is often highly expressed in various types of human cancers. However, the mechanistic basis of its oncogenic function, as well as the upstream regulatory pathway(s) that control Skp2 activities remains not fully understood. Recently, we repo...

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Detalles Bibliográficos
Autores principales: Wang, Zhiwei, Inuzuka, Hiroyuki, Zhong, Jiateng, Liu, Pengda, Sarkar, Fazlul H., Sun, Yi, Wei, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717793/
https://www.ncbi.nlm.nih.gov/pubmed/23230084