Suppression of Epithelial-to-Mesenchymal Transitioning Enhances Ex Vivo Reprogramming of Human Exocrine Pancreatic Tissue Toward Functional Insulin-Producing β-Like Cells

Because of the lack of tissue available for islet transplantation, new sources of β-cells have been sought for the treatment of type 1 diabetes. The aim of this study was to determine whether the human exocrine-enriched fraction from the islet isolation procedure could be reprogrammed to provide add...

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Detalles Bibliográficos
Autores principales: Lima, Maria João, Muir, Kenneth R., Docherty, Hilary M., Drummond, Robert, McGowan, Neil W.A., Forbes, Shareen, Heremans, Yves, Houbracken, Isabelle, Ross, James A., Forbes, Stuart J., Ravassard, Philippe, Heimberg, Harry, Casey, John, Docherty, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717833/
https://www.ncbi.nlm.nih.gov/pubmed/23610058
http://dx.doi.org/10.2337/db12-1256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717833/
https://www.ncbi.nlm.nih.gov/pubmed/23610058
http://dx.doi.org/10.2337/db12-1256

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