Identification of a Loss-of-Function Mutation in Ube2l6 Associated With Obesity Resistance

We previously mapped a locus on BALB/c chromosome 2 associated with protection from leptin-deficiency–induced obesity. Here, we generated the corresponding congenic mouse strain by introgression of a segment of C57BL/6J chromosome 2 to the BALB/c background to confirm the genotype–phenotype associat...

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Detalles Bibliográficos
Autores principales: Marcelin, Genevieve, Liu, Shun-Mei, Schwartz, Gary J., Chua, Streamson C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717837/
https://www.ncbi.nlm.nih.gov/pubmed/23557705
http://dx.doi.org/10.2337/db12-1054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717837/
https://www.ncbi.nlm.nih.gov/pubmed/23557705
http://dx.doi.org/10.2337/db12-1054

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