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Recovery From Overt Type 1 Diabetes Ensues When Immune Tolerance and β-Cell Formation Are Coupled With Regeneration of Endothelial Cells in the Pancreatic Islets

Immune modulation of pancreatic inflammation induces recovery from type 1 diabetes (T1D), but remission was not durable, perhaps because of an inability to sustain the formation and function of new pancreatic β-cells. We have previously shown that Ig-GAD2, carrying GAD 206–220 peptide, induced in hy...

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Detalles Bibliográficos
Autores principales: Wan, Xiaoxiao, Guloglu, F. Betul, VanMorlan, Amie M., Rowland, Linda M., Zaghouani, Sarah, Cascio, Jason A., Dhakal, Mermagya, Hoeman, Christine M., Zaghouani, Habib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717841/
https://www.ncbi.nlm.nih.gov/pubmed/23715620
http://dx.doi.org/10.2337/db12-1281