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PKCδ Impaired Vessel Formation and Angiogenic Factor Expression in Diabetic Ischemic Limbs

Decreased collateral vessel formation in diabetic peripheral limbs is characterized by abnormalities of the angiogenic response to ischemia. Hyperglycemia is known to activate protein kinase C (PKC), affecting the expression and activity of growth factors such as vascular endothelial growth factor (...

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Detalles Bibliográficos
Autores principales: Lizotte, Farah, Paré, Martin, Denhez, Benoit, Leitges, Michael, Guay, Andréanne, Geraldes, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717846/
https://www.ncbi.nlm.nih.gov/pubmed/23557702
http://dx.doi.org/10.2337/db12-1432