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Loss of Krüppel-Like Factor 3 (KLF3/BKLF) Leads to Upregulation of the Insulin-Sensitizing Factor Adipolin (FAM132A/CTRP12/C1qdc2)

Krüppel-like factor 3 (KLF3) is a transcriptional regulator that we have shown to be involved in the regulation of adipogenesis in vitro. Here, we report that KLF3-null mice are lean and protected from diet-induced obesity and glucose intolerance. On a chow diet, plasma levels of leptin are decrease...

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Detalles Bibliográficos
Autores principales: Bell-Anderson, Kim S., Funnell, Alister P., Williams, Helen, Mat Jusoh, Hanapi, Scully, Tiffany, Lim, Wooi F., Burdach, Jon G., Mak, Ka Sin, Knights, Alexander J., Hoy, Andrew J., Nicholas, Hannah R., Sainsbury, Amanda, Turner, Nigel, Pearson, Richard C., Crossley, Merlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717849/
https://www.ncbi.nlm.nih.gov/pubmed/23633521
http://dx.doi.org/10.2337/db12-1745