Inhibition of VEGFR-2 Reverses Type 1 Diabetes in NOD Mice by Abrogating Insulitis and Restoring Islet Function

The dysregulation of receptor tyrosine kinases (RTKs) in multiple cell types during chronic inflammation is indicative of their pathogenic role in autoimmune diseases. Among the many RTKs, vascular endothelial growth factor receptor (VEGFR) stands out for its multiple effects on immunity, vasculariz...

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Detalles Bibliográficos
Autores principales: Villalta, S. Armando, Lang, Jiena, Kubeck, Samantha, Kabre, Beniwende, Szot, Gregory L., Calderon, Boris, Wasserfall, Clive, Atkinson, Mark A., Brekken, Rolf A., Pullen, Nick, Arch, Robert H., Bluestone, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717875/
https://www.ncbi.nlm.nih.gov/pubmed/23835340
http://dx.doi.org/10.2337/db12-1619

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717875/
https://www.ncbi.nlm.nih.gov/pubmed/23835340
http://dx.doi.org/10.2337/db12-1619

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