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Microphthalmia Transcription Factor Regulates Pancreatic β-Cell Function

Precise regulation of β-cell function is crucial for maintaining blood glucose homeostasis. Pax6 is an essential regulator of β-cell–specific factors like insulin and Glut2. Studies in the developing eye suggest that Pax6 interacts with Mitf to regulate pigment cell differentiation. Here, we show th...

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Detalles Bibliográficos
Autores principales: Mazur, Magdalena A., Winkler, Marcus, Ganić, Elvira, Colberg, Jesper K., Johansson, Jenny K., Bennet, Hedvig, Fex, Malin, Nuber, Ulrike A., Artner, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717881/
https://www.ncbi.nlm.nih.gov/pubmed/23610061
http://dx.doi.org/10.2337/db12-1464