Whole exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma

The molecular foundations of lower-grade gliomas (LGGs)—astrocytoma, oligodendroglioma, and oligoastrocytoma—remain less well characterized than those of their fully malignant counterpart, glioblastoma. Mutations in isocitrate dehydrogenase 1 and 2 (IDH1/2) likely represent initiating pathogenic eve...

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Detalles Bibliográficos
Autores principales: Kannan, Kasthuri, Inagaki, Akiko, Silber, Joachim, Gorovets, Daniel, Zhang, Jianan, Kastenhuber, Edward R., Heguy, Adriana, Petrini, John H., Chan, Timothy A., Huse, Jason T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717947/
https://www.ncbi.nlm.nih.gov/pubmed/23104868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717947/
https://www.ncbi.nlm.nih.gov/pubmed/23104868

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