High-Throughput Chemical Screens Identify Disulfiram as an Inhibitor of Human Glioblastoma Stem Cells

Glioblastoma Multiforme (GBM) continues to have a poor patient prognosis despite optimal standard of care. Glioma stem cells (GSCs) have been implicated as the presumed cause of tumor recurrence and resistance to therapy. With this in mind, we screened a diverse chemical library of 2,000 compounds t...

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Detalles Bibliográficos
Autores principales: Hothi, Parvinder, Martins, Timothy J., Chen, LiPing, Deleyrolle, Loic, Yoon, Jae-Geun, Reynolds, Brent, Foltz, Greg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research: Complementary Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717950/
https://www.ncbi.nlm.nih.gov/pubmed/23165409

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717950/
https://www.ncbi.nlm.nih.gov/pubmed/23165409

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