Molecular logistics using cytocleavable polyrotaxanes for the reactivation of enzymes delivered in living cells

The intracellular delivery of enzymes is an essential methodology to extend their therapeutic application. Herein, we have developed dissociable supermolecule-enzyme polyelectrolyte complexes based on reduction-cleavable cationic polyrotaxanes (PRXs) for the reactivation of delivered enzymes. These...

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Detalles Bibliográficos
Autores principales: Tamura, Atsushi, Ikeda, Go, Seo, Ji-Hun, Tsuchiya, Koji, Yajima, Hirofumi, Sasaki, Yoshihiro, Akiyoshi, Kazunari, Yui, Nobuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718191/
https://www.ncbi.nlm.nih.gov/pubmed/23872688
http://dx.doi.org/10.1038/srep02252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718191/
https://www.ncbi.nlm.nih.gov/pubmed/23872688
http://dx.doi.org/10.1038/srep02252

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