Potentiating mGluR5 function with a positive allosteric modulator enhances adaptive learning

Metabotropic glutamate receptor 5 (mGluR5) plays important roles in modulating neural activity and plasticity and has been associated with several neuropathological disorders. Previous work has shown that genetic ablation or pharmacological inhibition of mGluR5 disrupts fear extinction and spatial r...

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Detalles Bibliográficos
Autores principales: Xu, Jian, Zhu, Yongling, Kraniotis, Stephen, He, Qionger, Marshall, John J., Nomura, Toshihiro, Stauffer, Shaun R., Lindsley, Craig W., Conn, P. Jeffrey, Contractor, Anis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718201/
https://www.ncbi.nlm.nih.gov/pubmed/23869026
http://dx.doi.org/10.1101/lm.031666.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718201/
https://www.ncbi.nlm.nih.gov/pubmed/23869026
http://dx.doi.org/10.1101/lm.031666.113

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