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Modulation of allostery by protein intrinsic disorder

Allostery is an intrinsic property of many globular proteins and enzymes that is indispensable for cellular regulatory and feedback mechanisms. Recent theoretical(1) and empirical(2) observations indicate that allostery is also manifest in intrinsically disordered proteins (IDPs), which account for...

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Detalles Bibliográficos
Autores principales: Ferreon, Allan Chris M., Ferreon, Josephine C., Wright, Peter E., Deniz, Ashok A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718496/
https://www.ncbi.nlm.nih.gov/pubmed/23783631
http://dx.doi.org/10.1038/nature12294