Sulfadiazine resistance in Toxoplasma gondii: no involvement of overexpression or polymorphisms in genes of therapeutic targets and ABC transporters

Several treatment failures have been reported for the treatment of toxoplasmic encephalitis, chorioretinitis, and congenital toxoplasmosis. Recently we found three Toxoplasma gondii strains naturally resistant to sulfadiazine and we developed in vitro two sulfadiazine resistant strains, RH-R(SDZ) an...

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Detalles Bibliográficos
Autores principales: Doliwa, Christelle, Escotte-Binet, Sandie, Aubert, Dominique, Sauvage, Virginie, Velard, Frédéric, Schmid, Aline, Villena, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: EDP Sciences 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718540/
https://www.ncbi.nlm.nih.gov/pubmed/23707894
http://dx.doi.org/10.1051/parasite/2013020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718540/
https://www.ncbi.nlm.nih.gov/pubmed/23707894
http://dx.doi.org/10.1051/parasite/2013020

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