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Long-Range Regulatory Synergy Is Required to Allow Control of the TAC1 Locus by MEK/ERK Signalling in Sensory Neurones

Changes in the expression of the neuropeptide substance P (SP) in different populations of sensory neurones are associated with the progression of chronic inflammatory disease. Thus, understanding the genomic and cellular mechanisms driving the expression of the TAC1 gene, which encodes SP, in senso...

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Detalles Bibliográficos
Autores principales: Shanley, Lynne, Davidson, Scott, Lear, Marissa, Thotakura, Anil Kumar, McEwan, Iain Joseph, Ross, Ruth A., MacKenzie, Alasdair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718575/
https://www.ncbi.nlm.nih.gov/pubmed/21160161
http://dx.doi.org/10.1159/000322010