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Azacytidine induces necrosis of multiple myeloma cells through oxidative stress

Azacytidine is an inhibitor of DNA methyltransferase and is known to be an anti-leukemic agent to induce cancer cell apoptosis. In the present study, multiple myeloma cells were treated with azacytidine at clinically relevant concentrations to induce necrosis through oxidative stress. Necrotic myelo...

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Detalles Bibliográficos
Autores principales: Tian, Enbing, Tang, Haiping, Xu, Renhua, Liu, Chongdong, Deng, Haiteng, Wang, Qingtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718702/
https://www.ncbi.nlm.nih.gov/pubmed/23764212
http://dx.doi.org/10.1186/1477-5956-11-24