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Azacytidine induces necrosis of multiple myeloma cells through oxidative stress
Azacytidine is an inhibitor of DNA methyltransferase and is known to be an anti-leukemic agent to induce cancer cell apoptosis. In the present study, multiple myeloma cells were treated with azacytidine at clinically relevant concentrations to induce necrosis through oxidative stress. Necrotic myelo...
Autores principales: | Tian, Enbing, Tang, Haiping, Xu, Renhua, Liu, Chongdong, Deng, Haiteng, Wang, Qingtao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718702/ https://www.ncbi.nlm.nih.gov/pubmed/23764212 http://dx.doi.org/10.1186/1477-5956-11-24 |
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