Impairment of Endothelial-Myocardial Interaction Increases the Susceptibility of Cardiomyocytes to Ischemia/Reperfusion Injury

Endothelial-myocardial interactions may be critically important for ischemia/reperfusion injury. Tetrahydrobiopterin (BH(4)) is a required cofactor for nitric oxide (NO) production by endothelial NO synthase (eNOS). Hyperglycemia (HG) leads to significant increases in oxidative stress, oxidizing BH(...

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Detalles Bibliográficos
Autores principales: Leucker, Thorsten M., Ge, Zhi-Dong, Procknow, Jesse, Liu, Yanan, Shi, Yang, Bienengraeber, Martin, Warltier, David C., Kersten, Judy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718730/
https://www.ncbi.nlm.nih.gov/pubmed/23894596
http://dx.doi.org/10.1371/journal.pone.0070088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718730/
https://www.ncbi.nlm.nih.gov/pubmed/23894596
http://dx.doi.org/10.1371/journal.pone.0070088

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