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Impairment of Endothelial-Myocardial Interaction Increases the Susceptibility of Cardiomyocytes to Ischemia/Reperfusion Injury
Endothelial-myocardial interactions may be critically important for ischemia/reperfusion injury. Tetrahydrobiopterin (BH(4)) is a required cofactor for nitric oxide (NO) production by endothelial NO synthase (eNOS). Hyperglycemia (HG) leads to significant increases in oxidative stress, oxidizing BH(...
Autores principales: | Leucker, Thorsten M., Ge, Zhi-Dong, Procknow, Jesse, Liu, Yanan, Shi, Yang, Bienengraeber, Martin, Warltier, David C., Kersten, Judy R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718730/ https://www.ncbi.nlm.nih.gov/pubmed/23894596 http://dx.doi.org/10.1371/journal.pone.0070088 |
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