In Vivo Neutralization of α-Cobratoxin with High-Affinity Llama Single-Domain Antibodies (V(H)Hs) and a V(H)H-Fc Antibody

Small recombinant antibody fragments (e.g. scFvs and V(H)Hs), which are highly tissue permeable, are being investigated for antivenom production as conventional antivenoms consisting of IgG or F(ab’)(2) antibody fragments do not effectively neutralize venom toxins located in deep tissues. However, a...

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Detalles Bibliográficos
Autores principales: Richard, Gabrielle, Meyers, Ashley J., McLean, Michael D., Arbabi-Ghahroudi, Mehdi, MacKenzie, Roger, Hall, J. Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718736/
https://www.ncbi.nlm.nih.gov/pubmed/23894495
http://dx.doi.org/10.1371/journal.pone.0069495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718736/
https://www.ncbi.nlm.nih.gov/pubmed/23894495
http://dx.doi.org/10.1371/journal.pone.0069495

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