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Identification of novel modulators for ionotropic glutamate receptor, iGluA2 by in-silico screening

BACKGROUND: Ionotropic glutamate receptors (iGluAs, IUPHAR nomenclature) are the major excitatory amino acid neurotransmitter receptors in the mammalian central nervous system (CNS). iGluAs are potential therapeutic drug targets for various neurological disorders including ischemia, epilepsy, Parkin...

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Detalles Bibliográficos
Autor principal: Padmanabhan, Balasundaram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718743/
https://www.ncbi.nlm.nih.gov/pubmed/23855825
http://dx.doi.org/10.1186/1742-4682-10-46