Cargando…
Identification of novel modulators for ionotropic glutamate receptor, iGluA2 by in-silico screening
BACKGROUND: Ionotropic glutamate receptors (iGluAs, IUPHAR nomenclature) are the major excitatory amino acid neurotransmitter receptors in the mammalian central nervous system (CNS). iGluAs are potential therapeutic drug targets for various neurological disorders including ischemia, epilepsy, Parkin...
Autor principal: | Padmanabhan, Balasundaram |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718743/ https://www.ncbi.nlm.nih.gov/pubmed/23855825 http://dx.doi.org/10.1186/1742-4682-10-46 |
Ejemplares similares
-
Genome-wide identification, characterization and classification of ionotropic glutamate receptor genes (iGluRs) in the malaria vector Anopheles sinensis (Diptera: Culicidae)
por: Wang, Ting-Ting, et al.
Publicado: (2018) -
Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology
por: Lemoine, Damien, et al.
Publicado: (2020) -
Cryo-EM Structures of the Ionotropic Glutamate Receptor GluD1 Reveal
a Non-Swapped Architecture
por: Burada, Ananth Prasad, et al.
Publicado: (2020) -
Structural Mechanisms of Gating in Ionotropic Glutamate
Receptors
por: Twomey, Edward C., et al.
Publicado: (2017) -
Targeting Ionotropic Glutamate Receptors in the Treatment of Epilepsy
por: Celli, Roberta, et al.
Publicado: (2021)