Conformational Behavior and Aggregation of Ataxin-3 in SDS

Spinocerebellar ataxia type 3 (SCA3) is one of nine polyglutamine (polyQ) diseases all characterized by the presence of intraneuronal inclusions that contain aggregated protein. Aggregation of ataxin-3, the causative protein of SCA3, has been well characterized in vitro, with both pathogenic and non...

Descripción completa

Detalles Bibliográficos
Autores principales: Saunders, Helen M., Hughes, Victoria A., Cappai, Roberto, Bottomley, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718759/
https://www.ncbi.nlm.nih.gov/pubmed/23894474
http://dx.doi.org/10.1371/journal.pone.0069416

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718759/
https://www.ncbi.nlm.nih.gov/pubmed/23894474
http://dx.doi.org/10.1371/journal.pone.0069416

Ejemplares similares