Rescue of Amyloid-Beta-Induced Inhibition of Nicotinic Acetylcholine Receptors by a Peptide Homologous to the Nicotine Binding Domain of the Alpha 7 Subtype

Alzheimer's disease (AD) is characterized by brain accumulation of the neurotoxic amyloid-β peptide (Aβ) and by loss of cholinergic neurons and nicotinic acetylcholine receptors (nAChRs). Recent evidence indicates that memory loss and cognitive decline in AD correlate better with the amount of...

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Detalles Bibliográficos
Autores principales: Nery, Arthur A., Magdesian, Margaret H., Trujillo, Cleber A., Sathler, Luciana B., Juliano, Maria A., Juliano, Luiz, Ulrich, Henning, Ferreira, Sergio T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718777/
https://www.ncbi.nlm.nih.gov/pubmed/23894286
http://dx.doi.org/10.1371/journal.pone.0067194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718777/
https://www.ncbi.nlm.nih.gov/pubmed/23894286
http://dx.doi.org/10.1371/journal.pone.0067194

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