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SVM-Based Prediction of Propeptide Cleavage Sites in Spider Toxins Identifies Toxin Innovation in an Australian Tarantula

Spider neurotoxins are commonly used as pharmacological tools and are a popular source of novel compounds with therapeutic and agrochemical potential. Since venom peptides are inherently toxic, the host spider must employ strategies to avoid adverse effects prior to venom use. It is partly for this...

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Detalles Bibliográficos
Autores principales: Wong, Emily S. W., Hardy, Margaret C., Wood, David, Bailey, Timothy, King, Glenn F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718798/
https://www.ncbi.nlm.nih.gov/pubmed/23894279
http://dx.doi.org/10.1371/journal.pone.0066279