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Epstein-Barr Virus Encoded dUTPase Containing Exosomes Modulate Innate and Adaptive Immune Responses in Human Dendritic Cells and Peripheral Blood Mononuclear Cells

We have recently demonstrated that Epstein-Barr virus (EBV)-encoded deoxyuridine triphosphate nucleotidohydrolase (dUTPase) modulates innate immunity in human primary monocyte-derived macrophages through toll-like receptor (TLR) 2 leading to NF-κB activation and the production of pro-inflammatory cy...

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Detalles Bibliográficos
Autores principales: Ariza, Maria Eugenia, Rivailler, Pierre, Glaser, Ronald, Chen, Min, Williams, Marshall V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718799/
https://www.ncbi.nlm.nih.gov/pubmed/23894549
http://dx.doi.org/10.1371/journal.pone.0069827